Compare Metronidazole vs. Tinidazole, which is better for uses like: Bacterial Vaginosis, Trich and Giardiasis. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Tinidazole 3.4/5 over Metronidazole 3.3/5 in overall satisfaction. Summary. Tinidazole was compared with metronidazole in a series of controlled, randomised trials involving 510 patients with symptomatic intestinal amoebiasis, 100 patients with amoebic liver abscess and 186 children with symptomatic giardiasis. Single-dose tinidazole is the best available treatment for giardiasis in children and adults, a new study shows. José M. Ordóñez-Mena, MSc, Dr. sc. hum, from the University of Oxford, United Kingdom, and colleagues published the results of their study November 27, 2017, in the Journal of Antimicrobial Chemotherapy. Tinidazole and metronidazole, unlike the other medications, require that the patient abstain from alcohol for 72 hours after dosing. In my experience, the biggest challenge in treating giardiasis is deciding when to consider it in the differential and when to test for it. Alcohol consumption while on metronidazole can result in side effects such as facial flushing, sweating, nausea, vomiting, palpitations, low blood pressure and headache (disulfiram-like reaction). If you have an allergy to tinidazole, metronidazole, or any other part of tinidazole. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives. You can't drink alcohol while on Flagyl (metronidazole), and for at least 3 days after you finish it. Side effects can include nausea, headache, stomach upset, and a metallic taste in your mouth. Tinidazole is a drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class. To compare the efficacy of two different doses of tinidazole with metronidazole for treatment of bacterial vaginosis and compare side effects of the drugs. Study design Women were randomized to metronidazole 500 mg BID, tinidazole 500 mg BID, or tinidazole 1 gm BID all for 7 days. Abstract. Sixty-three expatriate residents and travellers in Bangladesh, infected with Giardia lamblia, participated in two studies to compare the therapeutic efficacy of tinidazole and metronidazole.